Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987964 | 0.82 | PARN (0.37) | CNOT7PARNALDH1A1SMN1; SMN2AGTR1 | |
| SCHEMBL9707720 | 0.80 | AGTR1 (0.43) | AGTR1AGTR2DPP4 | |
| SCHEMBL9708586 | 0.80 | CNOT7 (0.53) | CNOT7PARNALDH1A1SMN1; SMN2GDA | |
| SCHEMBL7987958 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HPGDKMT2AAGTR1 | |
| SCHEMBL9707628 | 0.79 | AGTR1 (0.50) | AGTR1AGTR2DPP4 | |
| SCHEMBL9708173 | 0.79 | AGTR1 (0.41) | AGTR1AGTR2DPP4 | |
| SCHEMBL9707797 | 0.78 | DPP4 (0.41) | AGTR1AGTR2DPP4 | |
| SCHEMBL9707787 | 0.78 | CNOT7 (0.46) | CNOT7PARNALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL554897 | 0.78 | CNOT7 (0.61) | CNOT7PARNALDH1A1SMN1; SMN2GDA | |
| SCHEMBL9708752 | 0.78 | AGTR1 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |