Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986630 | 0.87 | TAAR1 (0.33) | ALOX5TAAR1MEN1ALDH1A1MAPT | |
| SCHEMBL7989894 | 0.80 | KMT2A (0.43) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL7976203 | 0.80 | KMT2A (0.43) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL7990397 | 0.76 | OPRD1 (0.42) | ALOX5TAAR1MEN1ALDH1A1MAPT | |
| SCHEMBL7990399 | 0.76 | OPRD1 (0.42) | ALOX5TAAR1MEN1ALDH1A1MAPT | |
| SCHEMBL7993925 | 0.73 | CYP2C19 (0.39) | CYP2C19 | |
| SCHEMBL7993697 | 0.69 | KMT2A (0.40) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL7989433 | 0.69 | KDM4E (0.43) | ALOX5ALDH1A1 | |
| SCHEMBL6445436 | 0.69 | CTSS (0.44) | ALOX5MEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7986420 | 0.68 | NPC1 (0.40) | MEN1ALDH1A1MAPTKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |