Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.40 |
| ▸ | CCND1 | P24385 | 4/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976203 | 1.00 | KMT2A (0.43) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7993697 | 0.88 | KMT2A (0.40) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL7988010 | 0.80 | ALOX5 (0.37) | KMT2AMEN1MAPTALDH1A1MAPK1 | |
| SCHEMBL7976201 | 0.77 | TACR1 (0.59) | — | |
| SCHEMBL7976198 | 0.77 | TACR1 (0.59) | — | |
| SCHEMBL7989362 | 0.73 | KDM4E (0.55) | KMT2AMEN1MAPTL3MBTL1CDK4 | |
| SCHEMBL23100765 | 0.73 | HTR2A (0.57) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL23100766 | 0.73 | HTR2A (0.57) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8141283 | 0.73 | KMT2A (0.47) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL7993925 | 0.73 | CYP2C19 (0.39) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |