Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | FLT1 | P17948 | 3/20 | 0.45 |
| ▸ | FLT4 | P35916 | 3/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7551303 | 0.94 | KDR (0.52) | KDRFLT1FLT4GRIN2BGRIN1 | |
| SCHEMBL7987884 | 0.91 | KDR (0.52) | KDRFLT1FLT4GRIN2BGRIN1 | |
| SCHEMBL7555532 | 0.90 | KDR (0.52) | KDRFLT1FLT4HTR6MAPK14 | |
| SCHEMBL7548593 | 0.89 | KDR (0.57) | KDRFLT1FLT4GRIN2BGRIN1 | |
| SCHEMBL7553655 | 0.87 | KDR (0.39) | KDRFLT1FLT4GRIN2BGRIN1 | |
| SCHEMBL7990841 | 0.86 | KDR (0.54) | KDRFLT1FLT4HTR6DRD2 | |
| SCHEMBL7551471 | 0.86 | KDR (0.49) | KDRFLT1FLT4DRD2HRH3 | |
| SCHEMBL7553508 | 0.85 | KDR (0.69) | KDRFLT1FLT4GRIN2BGRIN1 | |
| SCHEMBL7987168 | 0.85 | KDR (0.54) | KDRFLT1FLT4MAPK14 | |
| SCHEMBL7548475 | 0.84 | KDR (0.52) | KDRFLT1FLT4GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |