Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991879 | 0.92 | MAPT (0.51) | F2PLAUELANECTRB1PIN1 | |
| SCHEMBL7988102 | 0.89 | MAPT (0.54) | ARMAPTMEN1KMT2ARAB9A | |
| SCHEMBL7988557 | 0.87 | PIN1 (0.58) | PIN1KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7989862 | 0.87 | AR (0.54) | ALDH1A1ARMAPTMEN1KMT2A | |
| SCHEMBL28914603 | 0.87 | AR (0.54) | ALDH1A1ARMAPTMEN1KMT2A | |
| SCHEMBL7992024 | 0.87 | AR (0.58) | ARMAPTMEN1KMT2ARAB9A | |
| SCHEMBL7995168 | 0.86 | MAPT (0.51) | F2PLAUELANECTRB1ALDH1A1 | |
| SCHEMBL7988441 | 0.84 | AR (0.55) | ALDH1A1ARMAPTMEN1KMT2A | |
| SCHEMBL7977720 | 0.83 | AR (0.52) | ARMAPTMEN1KMT2ARAB9A | |
| SCHEMBL7995187 | 0.82 | AR (0.53) | ALDH1A1ARMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |