SCHEMBL7988352

SCHEMBL7988352

FC(C(F)(F)F)C(F)(F)Oc1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
TSHR P16473 1/20 0.60
HSD17B10 Q99714 1/20 0.60
KIF11 P52732 1/20 0.41
CETP P11597 1/20 0.39
CYP1A2 P05177 2/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
PKM P14618 1/20 0.36
CYP2C19 P33261 1/20 0.36
HDAC1 Q13547 3/20 0.36
HDAC2 Q92769 3/20 0.36
HDAC3 O15379 2/20 0.36
HDAC4 P56524 2/20 0.36
HDAC7 Q8WUI4 2/20 0.36
HDAC10 Q969S8 2/20 0.36
HDAC11 Q96DB2 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC9 Q9UKV0 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706601 0.88 TSHR (0.62) ALDH1A1TSHRHSD17B10CETPCYP1A2
SCHEMBL7980644 0.86 KIF11 (0.45) ALDH1A1TSHRHSD17B10KIF11CETP
SCHEMBL11679555 0.86 ALDH1A1 (0.69) ALDH1A1TSHRHSD17B10KDM4EMEN1
SCHEMBL7914123 0.77 ALDH1A1 (0.48) ALDH1A1TSHRHSD17B10CETPKDM4E
SCHEMBL1361753 0.77 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B10KIF11CETP
SCHEMBL6601005 0.77 ALDH1A1 (0.59) ALDH1A1TSHRHSD17B10CA1CA2
SCHEMBL7911156 0.76 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10CETPKDM4E
SCHEMBL7911934 0.76 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10CETPKDM4E
SCHEMBL306823 0.76 KIF11 (0.50) KIF11HDAC1HDAC2HDAC3HDAC4
SCHEMBL18293362 0.76 KIF11 (0.50) KIF11HDAC1HDAC2HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172093-B1 PESTICIDES, INSECTICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2001-01-09 US disclosed
US-5969147-A Substituted biphenyloxazolines BAYER AKTIENGESELLSCHAFT (DE) 1999-10-19 US disclosed