Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988749 | 0.87 | PDE4A (0.41) | ALDH1A1ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL7984681 | 0.87 | PDE4A (0.41) | ALDH1A1ADORA2AADORA1ABCG2PDE4A | |
| SCHEMBL7974584 | 0.86 | GAA (0.56) | ALDH1A1TSHRHSD17B10ADORA2AADORA1 | |
| SCHEMBL7985410 | 0.86 | PDE4A (0.41) | ALDH1A1HPGDADORA2AADORA1PDE4A | |
| SCHEMBL7987222 | 0.85 | PDE4A (0.49) | ALDH1A1GAAPDE4APDE4BPDE4C | |
| SCHEMBL7974194 | 0.85 | ABCG2 (0.48) | HPGDTSHRADORA2AGAAABCG2 | |
| SCHEMBL7974200 | 0.85 | PDE4A (0.42) | ALDH1A1ADORA1PDE4APDE4BPDE4C | |
| SCHEMBL7985850 | 0.85 | GAA (0.49) | ADORA2AADORA1GAAABCG2NR1H2 | |
| SCHEMBL7985577 | 0.84 | ABCG2 (0.46) | ALDH1A1SMN1; SMN2HPGDGAAABCG2 | |
| SCHEMBL7974314 | 0.82 | GAA (0.46) | SMN1; SMN2HPGDGAAABCG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |