Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | IDE | P14735 | 1/20 | 0.51 |
| ▸ | MPI | P34949 | 1/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3640753 | 0.87 | KDM4E (0.51) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL8001404 | 0.83 | AR (0.45) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL7254503 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL7999235 | 0.77 | AR (0.40) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL7997924 | 0.77 | AR (0.40) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL2268508 | 0.77 | AR (0.61) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL7998933 | 0.75 | AR (0.38) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL7988876 | 0.75 | GPR84 (0.40) | KDM4EALDH1A1ARHPGDTHRB | |
| SCHEMBL7998927 | 0.75 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTARHPGD | |
| SCHEMBL3641750 | 0.74 | KDM4E (0.51) | KDM4EALDH1A1MAPTARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |