Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908841 | 0.82 | ALDH1A1 (0.52) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL7317416 | 0.82 | TDP1 (0.58) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL4427648 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL29007688 | 0.78 | TDP1 (0.49) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL11695700 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRCYP3A4POLB | |
| SCHEMBL12190644 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL28061957 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCYP3A4POLB | |
| SCHEMBL27907819 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL3708148 | 0.77 | TDP1 (0.47) | ALDH1A1TDP1TSHRL3MBTL1CYP3A4 | |
| SCHEMBL28790797 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245716-B1 | LOW DOSAGE; NONPHYTOTOXIC | NIPPON SODA CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |