Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988807 | 0.92 | ADORA2A (0.45) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| SCHEMBL7988512 | 0.91 | MEN1 (0.45) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| SCHEMBL7992126 | 0.90 | NPC1 (0.46) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| SCHEMBL7989590 | 0.90 | MAPT (0.53) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| Hydrochloric Acid SCHEMBL7977698 | 0.89 | MAPT (0.53) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| SCHEMBL7991889 | 0.86 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1CYP2C9 | |
| SCHEMBL7977611 | 0.85 | MAPK1 (0.49) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| SCHEMBL7992215 | 0.84 | MAPT (0.55) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| Hydrochloric Acid SCHEMBL7988824 | 0.83 | MAPT (0.54) | MEN1KMT2AMAPTALDH1A1ADORA2A | |
| SCHEMBL7978123 | 0.83 | RAB9A (0.41) | MEN1KMT2AMAPTALDH1A1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | claimed |
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |