Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12671065 | 0.92 | HSD11B1 (0.37) | HSD11B1MAPTTHRB | |
| SCHEMBL7983862 | 0.86 | MAPT (0.36) | MAPTTHRB | |
| SCHEMBL12671172 | 0.86 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL7995022 | 0.86 | HSD11B1 (0.45) | HSD11B1 | |
| SCHEMBL7987994 | 0.83 | HSD11B1 (0.34) | HSD11B1MAPTTHRB | |
| SCHEMBL7993122 | 0.83 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL7991887 | 0.83 | HSD11B1 (0.37) | HSD11B1MAPT | |
| SCHEMBL12671096 | 0.82 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL12677397 | 0.81 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL7995019 | 0.80 | HSD11B1 (0.39) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |