Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993122 | 0.93 | HSD11B1 (0.36) | HSD11B1KIT | |
| SCHEMBL7985976 | 0.91 | HSD11B1 (0.38) | HSD11B1KIT | |
| SCHEMBL7981154 | 0.83 | HSD11B1 (0.36) | HSD11B1KIT | |
| SCHEMBL1417698 | 0.83 | SLC22A12 (0.38) | HSD11B1 | |
| SCHEMBL12671408 | 0.83 | EGLN2 (0.37) | — | |
| SCHEMBL12671096 | 0.83 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL7983930 | 0.82 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL12677300 | 0.81 | MAPK14 (0.36) | HSD11B1KIT | |
| SCHEMBL7988964 | 0.81 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL7981732 | 0.80 | HSD11B1 (0.47) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377923-B2 | Triazole derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105460-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | HSD11B1, HSD11B2, HSD3B1 | HSD11B1 1/4885KIT 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.