SCHEMBL7989252

SCHEMBL7989252

CCOC(=O)Cn1cc2c(n1)CC1CCC2N1C(=O)C(OC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.35
RET P07949 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KDM4E B2RXH2 1/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
GAA P10253 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7985907 0.81 L3MBTL1 (0.38) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL7989492 0.80 SMN1; SMN2 (0.40) RAB9ARETMEN1KMT2AKDM4E
SCHEMBL7993429 0.77 CHRM2 (0.36) KMT2AKDM4EALDH1A1LMNAMAPK1
SCHEMBL7988257 0.76 RAB9A (0.35) RAB9ARETKDM4ETSHRALDH1A1
SCHEMBL8137379 0.71 KCNH2 (0.41) RAB9ARETKDM4EALDH1A1MAPT
SCHEMBL7985658 0.67 CHRM2 (0.39) HTTGAA
Hydrochloric Acid SCHEMBL7987411 0.65 HTR2A (0.38) KMT2AALDH1A1LMNAMAPK1GAA
SCHEMBL28268013 0.64 KMT2A (0.36) MEN1KMT2AKDM4ETSHRALDH1A1
SCHEMBL7988472 0.62 RAB9A (0.37) RAB9ARETKDM4ELMNA
SCHEMBL22811848 0.62 RET (0.45) RAB9ARETALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed