Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL7989434 | 0.87 | HPGD (0.48) | PLA2G4BALDH1A1LMNAMAPTHPGD | |
| Morpholine SCHEMBL7985369 | 0.83 | NR1H4 (0.56) | PLA2G4BALDH1A1LMNAMAPTHPGD | |
| 1,4-Diethoxybenzene SCHEMBL10980721 | 0.82 | NQO1 (0.52) | ALDH1A1LMNAMAPTHPGDFKBP1A | |
| Terephthalic Acid SCHEMBL31728763 | 0.82 | TSHR (0.52) | ALDH1A1MAPTHPGDTSHRTP53 | |
| SCHEMBL177390 | 0.82 | PLA2G4B (0.82) | PLA2G4BALDH1A1PARP10TSHRTP53 | |
| SCHEMBL8972055 | 0.81 | PLA2G4B (0.79) | PLA2G4BALDH1A1PARP10TSHRTP53 | |
| Methyl Alcohol SCHEMBL38654507 | 0.81 | PLA2G4B (0.79) | PLA2G4BALDH1A1PARP10TSHRTP53 | |
| SCHEMBL28886147 | 0.81 | PLA2G4B (0.79) | PLA2G4BALDH1A1PARP10TSHRTP53 | |
| Benzene SCHEMBL27667496 | 0.81 | PLA2G4B (0.79) | PLA2G4BPARP10TSHRTP53HCRTR1 | |
| Benzoic Acid SCHEMBL11879027 | 0.80 | TSHR (0.48) | ALDH1A1LMNAMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |