Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL7988982 | 0.88 | RAB9A (0.46) | NR1H4KMT2ARXRARXRBSMN1; SMN2 | |
| SCHEMBL29505938 | 0.84 | KMT2A (0.75) | NR1H4KMT2ARXRARXRBSMN1; SMN2 | |
| SCHEMBL1333545 | 0.84 | KMT2A (0.75) | NR1H4KMT2ARXRARXRBSMN1; SMN2 | |
| SCHEMBL29505934 | 0.84 | KMT2A (0.75) | NR1H4KMT2ARXRARXRBSMN1; SMN2 | |
| Morpholine SCHEMBL7989270 | 0.83 | PLA2G4B (0.59) | RXRARXRBSMN1; SMN2TP53HPGD | |
| Hydrochloric Acid SCHEMBL30608606 | 0.83 | KMT2A (0.73) | NR1H4KMT2ARXRARXRBSMN1; SMN2 | |
| Morpholine SCHEMBL7984701 | 0.81 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2TP53PKMNFKB1 | |
| Isophthalic Acid SCHEMBL15570863 | 0.78 | KMO (0.51) | KMT2ASMN1; SMN2RAB9AHPGDLMNA | |
| Isophthalic Acid SCHEMBL15572812 | 0.78 | KMO (0.51) | KMT2ASMN1; SMN2RAB9AHPGDLMNA | |
| Benzoic Acid SCHEMBL11879027 | 0.78 | TSHR (0.48) | KMT2ASMN1; SMN2RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |