Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985671 | 0.79 | COMT (0.44) | KDM4ETDP1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL7982788 | 0.67 | COMT (0.44) | KDM4ETDP1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL8463407 | 0.66 | PSEN1 (0.32) | GAAHTTSMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL8303370 | 0.66 | GAA (0.31) | GAAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL461567 | 0.66 | PTGS2 (0.40) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8307889 | 0.65 | GAA (0.31) | GAA | |
| SCHEMBL8307113 | 0.65 | GAA (0.31) | GAA | |
| SCHEMBL10595276 | 0.64 | FLT1 (0.46) | GAAMAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL10668454 | 0.64 | RAB9A (0.46) | SMN1; SMN2PTGER1ALDH1A1MEN1KMT2A | |
| SCHEMBL8940979 | 0.64 | NPC1 (0.30) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262074-B1 | 4-Hetaroylpyrazol derivatives and the use thereof as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| CN-1235600-A | 4-hetaroylpyrazol derivatives | BASF AG (DE) | 1999-11-17 | — | — | CN | disclosed |