Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306995 | 0.87 | — | — | |
| SCHEMBL8307113 | 0.84 | GAA (0.31) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8307889 | 0.84 | GAA (0.31) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8940911 | 0.80 | RAB9A (0.31) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8303291 | 0.78 | ALDH1A1 (0.31) | GAAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL8308183 | 0.76 | NPC1 (0.31) | SMN1; SMN2 | |
| SCHEMBL8940887 | 0.76 | — | — | |
| SCHEMBL8941176 | 0.75 | NPC1 (0.30) | SMN1; SMN2 | |
| SCHEMBL8306874 | 0.75 | GAA (0.33) | GAAHTTSMN1; SMN2 | |
| SCHEMBL8303372 | 0.74 | MAPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629623-B1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| US-5587484-A | HALOGENATION; OXIDATION; SULFONATION; HERBICIDES | IDEMITSU KOSAN CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5468722-A | Herbicides for corn, wheat, barley | IDEMITSU KOSAN CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0629623-A1 | PYRAZOLE DERIVATIVE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-12-21 | — | — | EP | disclosed |