Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 2/20 | 0.52 |
| ▸ | MC5R | P33032 | 1/20 | 0.52 |
| ▸ | MC3R | P41968 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | CDK4 | P11802 | 3/20 | 0.47 |
| ▸ | CCND1 | P24385 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620106 | 0.84 | CDK4 (0.66) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL7976198 | 0.84 | TACR1 (0.59) | TACR1MMP9MMP8MMP14 | |
| SCHEMBL7976201 | 0.84 | TACR1 (0.59) | TACR1MMP9MMP8MMP14 | |
| SCHEMBL7990061 | 0.81 | NLN (0.49) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL2992113 | 0.80 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL4126005 | 0.80 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL21292830 | 0.80 | KDM4E (0.70) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL8345144 | 0.79 | TACR1 (0.69) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL8345148 | 0.79 | TACR1 (0.69) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL30230046 | 0.79 | TACR1 (0.69) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |