Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 17/20 | 0.66 |
| ▸ | CCND1 | P24385 | 17/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7617491 | 0.91 | CDK4 (0.62) | CDK4CCND1KDM4EMEN1LMNA | |
| SCHEMBL21292830 | 0.86 | KDM4E (0.70) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL2992113 | 0.86 | KDM4E (0.70) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL4126005 | 0.86 | KDM4E (0.70) | KDM4EMEN1LMNAMPOMAPT | |
| SCHEMBL24746732 | 0.85 | CDK4 (0.60) | CDK4CCND1CDK2 | |
| SCHEMBL8345144 | 0.84 | TACR1 (0.69) | CDK4KDM4EMEN1LMNAMPO | |
| SCHEMBL30230046 | 0.84 | TACR1 (0.69) | CDK4KDM4EMEN1LMNAMPO | |
| SCHEMBL8345148 | 0.84 | TACR1 (0.69) | CDK4KDM4EMEN1LMNAMPO | |
| Dl-Tryptophan SCHEMBL28590169 | 0.84 | KDM4E (0.76) | CDK4CCND1KDM4EMEN1LMNA | |
| SCHEMBL7989362 | 0.84 | KDM4E (0.55) | CDK4CCND1KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | COLE BRIDGET M (US) | 2002-07-11 | — | — | US | claimed |
| US-20020091090-A1 | Somatostatin antagonists and agonists | COLE BRIDGET M (US) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091090-A1 | Somatostatin antagonists and agonists | GHSR, GHRHR, SSTR3 | CDK4 708/4885CCND1 453/4885KDM4E 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.