Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 6/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.49 |
| ▸ | ITGAL | P20701 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976198 | 1.00 | TACR1 (0.59) | TACR1MMP9MMP8MMP14ALOX15 | |
| SCHEMBL7993694 | 0.87 | MMP2 (0.54) | TACR1MMP9MMP8MMP14ACE | |
| SCHEMBL7989362 | 0.84 | KDM4E (0.55) | TACR1MMP9MMP8MMP14 | |
| SCHEMBL7989539 | 0.83 | MMP9 (0.52) | TACR1MMP9MMP8MMP14CCKBR | |
| SCHEMBL7989529 | 0.83 | MMP9 (0.52) | TACR1MMP9MMP8MMP14CCKBR | |
| SCHEMBL3780103 | 0.82 | MMP9 (0.77) | TACR1MMP9MMP8MMP14ALOX15 | |
| SCHEMBL8200364 | 0.81 | TACR1 (0.86) | TACR1MMP9MMP8MMP14ALOX15 | |
| SCHEMBL8200367 | 0.81 | TACR1 (0.86) | TACR1MMP9MMP8MMP14ALOX15 | |
| SCHEMBL17870487 | 0.79 | NMBR (0.58) | TACR1ALOX15 | |
| SCHEMBL17870489 | 0.79 | NMBR (0.58) | TACR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |