Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28044678 | 0.81 | KEAP1 (0.52) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL7988528 | 0.80 | HPGD (0.64) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL3070158 | 0.79 | GRIA4 (0.47) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL5109982 | 0.79 | HPGD (0.49) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL3070153 | 0.79 | HPGD (0.41) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL19553857 | 0.79 | HPGD (0.49) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL27695913 | 0.78 | MAPT (0.42) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL12104966 | 0.76 | HPGD (0.39) | HPGDLMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL7758939 | 0.76 | HPGD (0.48) | HPGDLMNAHTTSMN1; SMN2NR3C2 | |
| SCHEMBL95330 | 0.74 | PGR (0.48) | HPGDLMNAHTTSMN1; SMN2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |