SCHEMBL7989448

SCHEMBL7989448

CCCC(C)OCCCc1c[nH]cn1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 10/20 0.35
HRH4 Q9H3N8 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999598 0.84 HRH3 (0.36) HRH3
SCHEMBL7991263 0.76 HRH3 (0.33) HRH3
SCHEMBL4376138 0.76 HRH3 (0.32) HRH3
SCHEMBL4385141 0.76 HRH3 (0.34) HRH3
SCHEMBL9999614 0.75 DNM1 (0.36)
SCHEMBL793540 0.75
SCHEMBL4383620 0.75 HRH3 (0.63) HRH3HRH4
SCHEMBL7991392 0.74 HRH3 (0.33) HRH3
SCHEMBL772467 0.74 GPR84 (0.35) HRH3
SCHEMBL7977259 0.74 TLR7 (0.36) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248765-B1 ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) 2001-06-19 US disclosed