Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989472 | 1.00 | KDM4E (0.33) | KDM4EMAPTGRM1GRM5MEN1 | |
| SCHEMBL7977980 | 0.79 | TP53 (0.33) | KDM4EGRM1GRM5IRAK4TP53 | |
| SCHEMBL23323316 | 0.74 | TP53 (0.42) | MAPTGRM1GRM5TP53LMNA | |
| SCHEMBL19287695 | 0.72 | KDM4E (0.36) | KDM4EMEN1IRAK4ADORA3ADORA2A | |
| SCHEMBL23323444 | 0.71 | PIK3CA (0.40) | MAPTMEN1LMNA | |
| SCHEMBL8020504 | 0.71 | IRAK4 (0.41) | IRAK4ADORA3ADORA2AADORA1CYP3A4 | |
| SCHEMBL8482705 | 0.70 | CYP2D6 (0.41) | KDM4EMAPTGRM1GRM5MEN1 | |
| SCHEMBL8482702 | 0.70 | ALDH1A1 (0.41) | KDM4EMAPTTP53LMNAADORA3 | |
| SCHEMBL8490623 | 0.70 | PRCP (0.46) | MEN1IRAK4ADORA3ADORA2AADORA1 | |
| SCHEMBL8490628 | 0.70 | PRCP (0.46) | MEN1IRAK4ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281221-B1 | Substituted 1,3-dioxan-5-ylamino-hererocyclic compounds, processes for their preparation and their use as pest control compositions | HOECHST SCERING AGREVO GMBH (DE) | 2001-08-28 | — | — | US | disclosed |
| EP-0836603-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002264-A1 | SUBSTITUTED 1,3-DIOXAN-5-YLAMINO HETEROCYCLIC COMPOUNDS, METHODS FOR PREPARING THEM AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-23 | — | — | WO | disclosed |