Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.60 |
| ▸ | RAF1 | P04049 | 2/20 | 0.60 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.60 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.60 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366542 | 0.99 | MAPK13 (0.59) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7995288 | 0.90 | MAPK13 (0.52) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7977996 | 0.89 | TRPV1 (0.49) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7988191 | 0.89 | NPBWR1 (0.53) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7995390 | 0.89 | MAPK14 (0.48) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL29093221 | 0.87 | PIN1 (0.69) | PIN1CYP1A2MAPK1CASP1CYP2C19 | |
| SCHEMBL28576642 | 0.86 | ERCC1 (0.55) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL6367621 | 0.85 | ERCC1 (0.54) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7989517 | 0.85 | MAPT (0.49) | MAPK13RAF1MAPK12MAPK11MAPK14 | |
| SCHEMBL7977712 | 0.84 | MAPK14 (0.48) | MAPK13RAF1MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |