Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.83 |
| ▸ | POLB | P06746 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989269 | 1.00 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL11356824 | 1.00 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1045922 | 1.00 | LMNA (0.83) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1045984 | 0.93 | ALDH1A1 (0.74) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL1045595 | 0.93 | ALDH1A1 (0.74) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8529470 | 0.91 | ALDH1A1 (1.00) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL15901736 | 0.91 | ALDH1A1 (0.71) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13381620 | 0.91 | LMNA (1.00) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL82686 | 0.91 | LMNA (0.71) | LMNAALDH1A1POLBMEN1KMT2A | |
| SCHEMBL13215736 | 0.91 | ALDH1A1 (0.70) | LMNAALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288224-B1 | Preparation of n-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and n-arylethyl-ethanolamine sulphonate esters as intermediates | NYCOMED SALUTAR, INC. | 2001-09-11 | — | — | US | disclosed |
| US-6048979-A | CYCLOTETRAMERIZING, CLEAVAGE OF ARYLMETHYL GROUPS TO PREPARE CYCLEN AND DERIVATIVES | NYCOMED SALUTAR, INC. (US) | 2000-04-11 | — | — | US | disclosed |