SCHEMBL15901736

SCHEMBL15901736

Cc1ccc(CN2CCN(Cc3ccc(Cl)cc3)CC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
LMNA P02545 1/20 0.71
POLB P06746 1/20 0.71
SIGMAR1 Q99720 1/20 0.68
KDM4E B2RXH2 3/20 0.64
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
LSS P48449 1/20 0.58
MAPK1 P28482 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MAPT P10636 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045922 0.91 LMNA (0.83) ALDH1A1LMNAPOLBSIGMAR1MEN1
SCHEMBL11356824 0.91 LMNA (0.83) ALDH1A1LMNAPOLBSIGMAR1MEN1
SCHEMBL7989269 0.91 LMNA (0.83) ALDH1A1LMNAPOLBSIGMAR1MEN1
SCHEMBL7989530 0.91 LMNA (0.83) ALDH1A1LMNAPOLBSIGMAR1MEN1
SCHEMBL6031775 0.89 MAPT (0.71) ALDH1A1LMNAPOLBSIGMAR1KDM4E
SCHEMBL6031671 0.89 MAPT (0.71) ALDH1A1LMNAPOLBSIGMAR1KDM4E
Bromide SCHEMBL6031230 0.88 MAPT (0.69) ALDH1A1LMNAPOLBSIGMAR1KDM4E
SCHEMBL1045595 0.85 ALDH1A1 (0.74) ALDH1A1LMNAPOLBKDM4EMEN1
SCHEMBL1045984 0.85 ALDH1A1 (0.74) ALDH1A1LMNAPOLBKDM4EMEN1
SCHEMBL22802248 0.84 ALDH1A1 (0.72) ALDH1A1LMNAPOLBSIGMAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140212453-A1 SNACK SYSTEM, INCLUDING INTERIOR FILING OF INGREDIENT, OUTER COATING OF INGREDIENT, ADDITION OF INGREDIENT, AND FORMATION OF SNACK ROLL CHANG ALICE (US) 2014-07-31 US claimed
US-20140212453-A1 SNACK SYSTEM, INCLUDING INTERIOR FILING OF INGREDIENT, OUTER COATING OF INGREDIENT, ADDITION OF INGREDIENT, AND FORMATION OF SNACK ROLL CHANG ALICE (US) 2014-07-31 US disclosed