Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977691 | 0.89 | PRKAB2 (0.46) | MAPTTP53CHEK2GCGRMEN1 | |
| SCHEMBL7988623 | 0.87 | ALOX5 (0.52) | ALOX5MAPTTP53MAPK13MAPK12 | |
| SCHEMBL7991760 | 0.86 | PRKAB2 (0.44) | MAPTTP53CHEK2MEN1KMT2A | |
| SCHEMBL7991891 | 0.86 | PRKAB2 (0.44) | MAPTTP53CHEK2MEN1KMT2A | |
| SCHEMBL7989419 | 0.83 | MAPT (0.48) | MAPTTP53CHEK2GCGRMEN1 | |
| SCHEMBL7989935 | 0.83 | MAPT (0.48) | MAPTTP53CHEK2GCGRMEN1 | |
| SCHEMBL7977622 | 0.82 | DHODH (0.58) | CHEK2MEN1KMT2ADHODH | |
| SCHEMBL7977456 | 0.81 | DHODH (0.44) | MAPTMEN1KMT2ADHODHALDH1A1 | |
| SCHEMBL7988204 | 0.81 | ALDH1A1 (0.53) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL7977351 | 0.78 | PDE3B (0.43) | MAPTCHEK2MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |