Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309270 | 0.88 | L3MBTL1 (0.60) | HTTL3MBTL1MEN1KMT2ACYP1A2 | |
| 1,2-Diisopentoxybenzene SCHEMBL2843498 | 0.86 | HTT (0.62) | HTTL3MBTL1ALDH1A1LMNAIDO1 | |
| 1-Isopentoxy-2-Ethoxybenzene SCHEMBL2844377 | 0.82 | L3MBTL1 (0.56) | HTTL3MBTL1CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL18309273 | 0.82 | L3MBTL1 (0.55) | HTTL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL2903384 | 0.82 | L3MBTL1 (0.55) | HTTL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL27555722 | 0.82 | HTT (0.49) | HTTL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL10224215 | 0.81 | L3MBTL1 (0.58) | HTTL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL6479795 | 0.81 | L3MBTL1 (0.54) | HTTL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL9226775 | 0.81 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1290474 | 0.81 | KDM4E (0.61) | L3MBTL1MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071475-A1 | UREA DERIVATIVES HAVING PI3K-INHIBITING ACTIVITY | MTOR, STAT3, SLC14A1 | HTT 2761/4885L3MBTL1 1733/4885MEN1 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.