Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 5/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 3/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002404 | 0.95 | PYGL (0.37) | PYGLCYP51A1BCAT1GHSRDRD2 | |
| SCHEMBL7996254 | 0.88 | STAT6 (0.37) | PYGLCYP51A1GHSRDRD3ALOX15 | |
| SCHEMBL7998247 | 0.86 | STAT6 (0.33) | PYGLCYP51A1DRD2DRD3SMYD3 | |
| SCHEMBL4341339 | 0.86 | PYGL (0.39) | PYGLCYP51A1BCAT1GHSRDRD2 | |
| SCHEMBL7999763 | 0.84 | CYP51A1 (0.35) | PYGLCYP51A1BCAT1DRD2ALOX15 | |
| SCHEMBL8002402 | 0.82 | STAT6 (0.37) | PYGLCYP51A1BCAT1GHSRALOX15 | |
| SCHEMBL8004923 | 0.81 | PYGL (0.37) | PYGLCYP51A1BCAT1DRD2DRD3 | |
| SCHEMBL8002978 | 0.81 | TDP1 (0.35) | PYGLCYP51A1BCAT1DRD2DRD3 | |
| SCHEMBL4341295 | 0.81 | POLB (0.41) | PYGLCYP51A1GHSRDRD3ALOX15 | |
| SCHEMBL4336622 | 0.81 | POLB (0.41) | PYGLCYP51A1GHSRDRD3ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146182-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-03 | — | — | WO | disclosed |