Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 5/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.34 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996254 | 0.95 | STAT6 (0.37) | STAT6CYP51A1PYGLSMYD3GHSR | |
| SCHEMBL8002978 | 0.91 | TDP1 (0.35) | STAT6CYP51A1PYGLSMYD3HTRA1 | |
| SCHEMBL7999763 | 0.90 | CYP51A1 (0.35) | STAT6CYP51A1PYGLSMYD3HTRA1 | |
| SCHEMBL8002404 | 0.88 | PYGL (0.37) | CYP51A1PYGLSMYD3GHSRALOX15 | |
| SCHEMBL4338819 | 0.86 | STAT6 (0.40) | STAT6CYP51A1PYGLSMYD3GHSR | |
| SCHEMBL7998247 | 0.86 | STAT6 (0.33) | STAT6CYP51A1PYGLSMYD3HTRA1 | |
| SCHEMBL7989864 | 0.82 | PYGL (0.37) | CYP51A1PYGLSMYD3GHSRALOX15 | |
| SCHEMBL8004923 | 0.82 | PYGL (0.37) | CYP51A1PYGLSMYD3ALOX15BCAT1 | |
| SCHEMBL4343831 | 0.82 | STAT6 (0.39) | STAT6CYP51A1PYGLSMYD3HTRA1 | |
| SCHEMBL4350448 | 0.81 | STAT6 (0.40) | STAT6CYP51A1PYGLSMYD3HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146182-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-03 | — | — | WO | disclosed |