Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988458 | 0.82 | GABRA2 (0.49) | RAB9AMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7977729 | 0.82 | MEN1 (0.48) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6257997 | 0.78 | CYP1A2 (0.62) | RAB9ANPC1MAPTCYP1A2CYP2C9 | |
| SCHEMBL13247931 | 0.74 | HDAC8 (0.56) | CYP1A2CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7988918 | 0.74 | RAB9A (0.47) | RAB9ANPC1MAPTCYP1A2CYP2C9 | |
| SCHEMBL3405737 | 0.73 | MAPK1 (0.59) | RAB9AMAPTCYP1A2SMN1; SMN2MAPK1 | |
| SCHEMBL7987898 | 0.72 | CYP19A1 (0.56) | SMN1; SMN2ALDH1A1GABRA2GABRB2MEN1 | |
| SCHEMBL8823134 | 0.71 | GABRA2 (0.50) | RAB9ANPC1MAPTCYP1A2CYP2C9 | |
| SCHEMBL3402362 | 0.71 | MAPK1 (0.51) | RAB9AMAPTSMN1; SMN2MAPK1HCRTR1 | |
| SCHEMBL7989585 | 0.71 | TARBP2 (0.46) | RAB9ANPC1MAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |