Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987898 | 0.84 | CYP19A1 (0.56) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL7989910 | 0.82 | RAB9A (0.49) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL7989365 | 0.82 | MEN1 (0.52) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL6274152 | 0.79 | GABRA2 (0.59) | GABRA2GABRB2ALDH1A1HSD17B10CYP19A1 | |
| SCHEMBL7989585 | 0.76 | TARBP2 (0.46) | GABRA2GABRB2GABRG2GABRB3GABRA5 | |
| SCHEMBL3400011 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HSD17B10ELANEKDM4EMAPK1 | |
| SCHEMBL7989677 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EMAPK1KMT2AL3MBTL1 | |
| SCHEMBL8823098 | 0.72 | GABRA2 (0.51) | GABRA2GABRB2ALDH1A1CYP19A1KDM4E | |
| SCHEMBL13247931 | 0.72 | HDAC8 (0.56) | KDM4EKMT2ACDC25BCDC25ACDC25C | |
| SCHEMBL5548693 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HSD17B10ELANEKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |