Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990034 | 1.00 | MMP3 (0.50) | MMP3ALOX5ALOX5APDHODHMAPT | |
| SCHEMBL7399256 | 0.81 | MMP3 (0.43) | MMP3ALOX5ALOX5APMAPTL3MBTL1 | |
| SCHEMBL7399254 | 0.81 | MMP3 (0.43) | MMP3ALOX5ALOX5APMAPTL3MBTL1 | |
| SCHEMBL7993490 | 0.76 | MMP3 (0.78) | MMP3MAPTMCL1PTGER4 | |
| SCHEMBL7996980 | 0.75 | MMP3 (0.69) | MMP3MAPTL3MBTL1MCL1 | |
| SCHEMBL9043523 | 0.69 | PTPRC (0.49) | MAPT | |
| SCHEMBL9043517 | 0.69 | PTPRC (0.49) | MAPT | |
| SCHEMBL27752593 | 0.69 | AOC3 (0.49) | — | |
| SCHEMBL7996733 | 0.69 | MMP3 (0.49) | MMP3MAPTL3MBTL1TRPM4 | |
| SCHEMBL7991540 | 0.68 | MMP3 (0.76) | MMP3MAPTL3MBTL1MCL1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |