Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487118 | 0.87 | MMP3 (0.65) | MMP3MAPTKMT2AMEN1NPC1 | |
| SCHEMBL7991703 | 0.83 | MMP3 (0.43) | MMP3MAPTKMT2AMEN1NPC1 | |
| SCHEMBL11646131 | 0.79 | MAPT (0.62) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6562825 | 0.78 | ALDH1A1 (0.66) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL7990560 | 0.77 | MMP3 (0.79) | MMP3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7990117 | 0.75 | MMP3 (0.61) | MMP3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7990113 | 0.75 | MMP3 (0.61) | MMP3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5404802 | 0.74 | ALDH1A1 (0.52) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL10935027 | 0.74 | ALDH1A1 (0.52) | MMP3KMT2AMEN1RAB9ACTSD | |
| SCHEMBL27628199 | 0.74 | MAPT (0.73) | MAPTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |