Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399256 | 1.00 | MMP3 (0.43) | MMP3PTGESMAOBPDE10AMEN1 | |
| SCHEMBL7990037 | 0.81 | MMP3 (0.50) | MMP3PTGESMAPTALOX5APL3MBTL1 | |
| SCHEMBL7990034 | 0.81 | MMP3 (0.50) | MMP3PTGESMAPTALOX5APL3MBTL1 | |
| SCHEMBL7996795 | 0.73 | MMP3 (0.66) | MMP3MAPTL3MBTL1TDP1RXFP1 | |
| SCHEMBL7990497 | 0.72 | MAOB (0.48) | MAOBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL7990495 | 0.72 | MAOB (0.48) | MAOBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL7399437 | 0.70 | MAOB (0.51) | MAOBMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL27752593 | 0.70 | AOC3 (0.49) | CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL3267323 | 0.70 | MAOB (0.48) | MAOBMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL3267319 | 0.70 | MAOB (0.48) | MAOBMAPTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |
| WO-2000037433-A1 | INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-06-29 | — | — | WO | disclosed |