Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990372 | 1.00 | ALDH1A1 (0.33) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7994208 | 0.86 | DPP4 (0.47) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7994206 | 0.86 | DPP4 (0.47) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7975696 | 0.83 | SLC7A5 (0.39) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7975699 | 0.83 | SLC7A5 (0.39) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7989844 | 0.82 | DPP4 (0.34) | ALDH1A1DPP4TSHR | |
| SCHEMBL7990335 | 0.82 | DPP4 (0.34) | ALDH1A1DPP4TSHR | |
| SCHEMBL7986467 | 0.81 | DPP4 (0.46) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7986296 | 0.81 | DPP4 (0.49) | ALDH1A1MAPTLMNAABCC4NOS3 | |
| SCHEMBL7986473 | 0.81 | DPP4 (0.46) | ALDH1A1MAPTLMNAABCC4NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |