Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975699 | 1.00 | SLC7A5 (0.39) | SLC7A5NOS3NOS1NOS2SLC1A3 | |
| SCHEMBL7990370 | 0.83 | ALDH1A1 (0.33) | NOS3NOS1NOS2ALDH1A1LMNA | |
| SCHEMBL7990372 | 0.83 | ALDH1A1 (0.33) | NOS3NOS1NOS2ALDH1A1LMNA | |
| SCHEMBL7994206 | 0.81 | DPP4 (0.47) | SLC7A5NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL7994208 | 0.81 | DPP4 (0.47) | SLC7A5NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL7986250 | 0.80 | NOS3 (0.39) | NOS3NOS1NOS2SLC1A3SLC1A2 | |
| SCHEMBL7986244 | 0.80 | NOS3 (0.39) | NOS3NOS1NOS2SLC1A3SLC1A2 | |
| SCHEMBL7990335 | 0.77 | DPP4 (0.34) | ALDH1A1 | |
| SCHEMBL7989844 | 0.77 | DPP4 (0.34) | ALDH1A1 | |
| SCHEMBL7990404 | 0.77 | PSEN1 (0.37) | ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |