Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990335 | 1.00 | DPP4 (0.34) | DPP4DPP8DPP9DPP7ALDH1A1 | |
| SCHEMBL7994206 | 0.86 | DPP4 (0.47) | DPP4ALDH1A1 | |
| SCHEMBL7994208 | 0.86 | DPP4 (0.47) | DPP4ALDH1A1 | |
| SCHEMBL7990370 | 0.82 | ALDH1A1 (0.33) | DPP4ALDH1A1TSHR | |
| SCHEMBL7990372 | 0.82 | ALDH1A1 (0.33) | DPP4ALDH1A1TSHR | |
| SCHEMBL7986467 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1TSHR | |
| SCHEMBL7986473 | 0.81 | DPP4 (0.46) | DPP4ALDH1A1TSHR | |
| SCHEMBL7975696 | 0.77 | SLC7A5 (0.39) | ALDH1A1 | |
| SCHEMBL7975699 | 0.77 | SLC7A5 (0.39) | ALDH1A1 | |
| SCHEMBL7986244 | 0.76 | NOS3 (0.39) | DPP4DPP8DPP9DPP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |