Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 4/20 | 0.45 |
| ▸ | FNTB | P49356 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248175 | 0.87 | LMNA (0.63) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL29015206 | 0.85 | USP2 (0.74) | LMNANPC1L1USP2FNTAFNTB | |
| SCHEMBL14924215 | 0.85 | USP2 (0.74) | LMNANPC1L1USP2FNTAFNTB | |
| SCHEMBL863638 | 0.85 | USP2 (0.74) | LMNANPC1L1USP2FNTAFNTB | |
| SCHEMBL4739371 | 0.83 | GPBAR1 (0.66) | LMNAUSP2GPBAR1EPHA2AKR1B10 | |
| SCHEMBL29289385 | 0.82 | GPBAR1 (0.69) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL23483128 | 0.81 | GPBAR1 (0.58) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL29289387 | 0.81 | GPBAR1 (0.58) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL26653759 | 0.81 | NPC1L1 (0.60) | LMNANPC1L1USP2GPBAR1EPHA2 | |
| SCHEMBL10683655 | 0.80 | LMNA (0.45) | LMNANPC1L1USP2GPBAR1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274118-B1 | INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE | NORDION INTERNATIONAL INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| WO-1995002424-A1 | LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN | NORDION INTERNATIONAL INC. (CA) | 1995-01-26 | — | — | WO | disclosed |
| US-4212815-A | REACTING A KETONE WITH AN N,N-DISUBSTITUTED AMINOSULFUR TRIFLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-15 | — | — | US | disclosed |