SCHEMBL248175

SCHEMBL248175

CC(CO)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC(=O)C4CCCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.63
NPC1L1 Q9UHC9 2/20 0.63
USP2 O75604 1/20 0.63
OSBP P22059 2/20 0.55
NR1H3 Q13133 1/20 0.55
RORC P51449 1/20 0.55
GPR183 P32249 2/20 0.50
GPBAR1 Q8TDU6 2/20 0.49
AKR1B10 O60218 1/20 0.49
AKR1B1 P15121 1/20 0.49
EFNA1 P20827 1/20 0.49
EPHA2 P29317 1/20 0.49
PSEN1 P49768 1/20 0.49
PSEN2 P49810 1/20 0.49
APH1B Q8WW43 1/20 0.49
NCSTN Q92542 1/20 0.49
APH1A Q96BI3 1/20 0.49
PSENEN Q9NZ42 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL863638 0.90 USP2 (0.74) LMNANPC1L1USP2OSBPRORC
SCHEMBL29015206 0.90 USP2 (0.74) LMNANPC1L1USP2OSBPRORC
SCHEMBL14924215 0.90 USP2 (0.74) LMNANPC1L1USP2OSBPRORC
SCHEMBL13076840 0.87 NPC1L1 (0.83) LMNANPC1L1USP2OSBPNR1H3
SCHEMBL7990443 0.87 LMNA (0.58) LMNANPC1L1USP2OSBPNR1H3
SCHEMBL27730341 0.87 LMNA (0.56) LMNANPC1L1USP2GPBAR1AKR1B10
SCHEMBL1517837 0.87 LMNA (0.56) LMNANPC1L1USP2GPBAR1AKR1B10
SCHEMBL26653759 0.85 NPC1L1 (0.60) LMNANPC1L1USP2OSBPNR1H3
SCHEMBL28271545 0.85 NPC1L1 (0.57) LMNANPC1L1USP2GPBAR1AKR1B10
SCHEMBL29289385 0.85 GPBAR1 (0.69) LMNANPC1L1USP2GPBAR1AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 927 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062716-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS POPVAX PRIVATE LTD (IN) 2026-03-05 US claimed
EP-4577196-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS Popvax Private Limited (IN) 2025-07-02 EP claimed
WO-2025052180-A2 LIPIDS AND LIPID NANOPARTICLES Axelyf ehf. (IS) 2025-03-13 WO claimed
WO-2024044178-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS POPVAX PRIVATE LIMITED (IN) 2024-02-29 WO claimed
EP-3368024-B1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES INC (US) 2023-09-20 EP claimed
US-20220054429-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES, INC. 2022-02-24 US claimed
EP-2411052-B1 CARRIER COMPRISING A VITAMIN E DERIVATIVE AND ANNEXIN V UCL BUSINESS LTD (GB) 2020-10-07 EP claimed
US-20180311182-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES, INC. 2018-11-01 US claimed
EP-3368024-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER Jay Pharma, Inc. (CA) 2018-09-05 EP claimed
WO-2017072773-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER NATHAN ILANA (IL) 2017-05-04 WO claimed
US-9580711-B2 Lipid particles with asymmetric cationic lipids for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2017-02-28 US claimed
US-9545392-B2 Carrier comprising a vitamin E derivative UCL BUSINESS PLC (GB) 2017-01-17 US claimed
US-20160244761-A1 LIPID PARTICLES WITH ASYMMETRIC CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2016-08-25 US claimed
US-20120115771-A1 CARRIER UCL BUSINESS PLC (GB) 2012-05-10 US claimed
EP-2411052-A2 CARRIER COMPRISING A VITAMIN E DERIVATIVE UCL Business PLC (GB) 2012-02-01 EP claimed
WO-2010109212-A2 CARRIER UCL BUSINESS PLC (GB) 2010-09-30 WO claimed
US-12637422-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2026-05-26 US disclosed
WO-2026102141-A1 COMPOSITIONS FOR PCSK9 GENE EDITING AND METHODS OF USING SAME FOR TREATMENT OF DISEASE VERVE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-6274118-B1 INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE NORDION INTERNATIONAL INC. (CA) 2001-08-14 US disclosed
WO-1995002424-A1 LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN NORDION INTERNATIONAL INC. (CA) 1995-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062716-A1 LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS CETP, PLTP, LDLR LMNA 123/4885NPC1L1 5/4885USP2 3448/4885
US-12637422-B2 Ionizable cationic lipid for RNA delivery POLRMT, SLC27A1, SLC43A1 LMNA 287/4885NPC1L1 6/4885USP2 4022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.