Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 8/20 | 0.44 |
| ▸ | EDNRA | P25101 | 11/20 | 0.42 |
| ▸ | EDNRB | P24530 | 4/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990488 | 0.90 | DHPS (0.52) | DHPSEDNRA | |
| SCHEMBL7996803 | 0.86 | EDNRA (0.48) | DHPSEDNRAEDNRBIRAK4 | |
| SCHEMBL7993822 | 0.83 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL7993509 | 0.81 | DHPS (0.49) | DHPSEDNRAEDNRB | |
| SCHEMBL4066782 | 0.81 | DHPS (0.66) | DHPSEDNRAEDNRB | |
| SCHEMBL2640202 | 0.80 | EDNRA (0.52) | DHPSEDNRAEDNRB | |
| SCHEMBL7997001 | 0.78 | EDNRA (0.51) | EDNRAEDNRBIRAK4 | |
| SCHEMBL7979324 | 0.77 | DHPS (0.50) | DHPSEDNRAEDNRB | |
| SCHEMBL7993551 | 0.76 | EDNRA (0.49) | DHPSEDNRAEDNRBIRAK4 | |
| SCHEMBL7996807 | 0.76 | DHPS (0.53) | DHPSEDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |