Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 9/20 | 0.48 |
| ▸ | EDNRB | P24530 | 6/20 | 0.48 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.46 |
| ▸ | DHPS | P49366 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997001 | 0.90 | EDNRA (0.51) | EDNRAEDNRBIRAK4 | |
| SCHEMBL7996807 | 0.89 | DHPS (0.53) | EDNRAEDNRBDHPS | |
| SCHEMBL7993551 | 0.89 | EDNRA (0.49) | EDNRAEDNRBIRAK4DHPSPOLB | |
| SCHEMBL7997029 | 0.88 | EDNRA (0.49) | EDNRAEDNRBIRAK4DHPSMAPT | |
| SCHEMBL7990484 | 0.86 | DHPS (0.44) | EDNRAEDNRBIRAK4DHPS | |
| SCHEMBL7993866 | 0.84 | EDNRB (0.55) | EDNRAEDNRBIRAK4DHPSMAPT | |
| SCHEMBL7997031 | 0.83 | EDNRB (0.59) | EDNRAEDNRBIRAK4DHPSPOLB | |
| SCHEMBL7993509 | 0.82 | DHPS (0.49) | EDNRAEDNRBDHPS | |
| SCHEMBL4066782 | 0.82 | DHPS (0.66) | EDNRAEDNRBDHPS | |
| SCHEMBL7993822 | 0.81 | IRAK4 (0.54) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081338-A1 | SUBSTITUTED SULFONYLAMINOPYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2001-11-01 | — | — | WO | disclosed |