Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988163 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1TACR1SCN9AMAPT | |
| SCHEMBL7994280 | 0.94 | TACR1 (0.46) | SMN1; SMN2MAPK1TACR1 | |
| SCHEMBL7976826 | 0.94 | MAPK1 (0.45) | SMN1; SMN2MAPK1MEN1KMT2ABCHE | |
| SCHEMBL7986645 | 0.92 | TACR1 (0.45) | SMN1; SMN2MAPK1TACR1 | |
| SCHEMBL7986462 | 0.92 | MAPK1 (0.44) | SMN1; SMN2MAPK1MEN1KMT2ABCHE | |
| SCHEMBL8810898 | 0.91 | TACR1 (0.47) | SMN1; SMN2MAPK1TACR1MAPTTP53 | |
| SCHEMBL8807798 | 0.90 | MAPK1 (0.46) | SMN1; SMN2MAPK1SCN9AMMP2MMP9 | |
| SCHEMBL7993751 | 0.88 | TACR1 (0.48) | SMN1; SMN2MAPK1TACR1MAPTTP53 | |
| SCHEMBL7990070 | 0.88 | MAPK1 (0.47) | SMN1; SMN2MAPK1SCN9AMEN1KMT2A | |
| SCHEMBL7989806 | 0.84 | EDNRA (0.40) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |