Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.35 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.35 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990527 | 0.84 | LMNA (0.41) | LMNAALDH1A1HDAC6TP53MAPT | |
| SCHEMBL7465767 | 0.83 | LMNA (0.43) | LMNAALDH1A1HDAC6TP53MAPT | |
| SCHEMBL7472407 | 0.73 | ALDH1A1 (0.39) | LMNAALDH1A1HDAC6TP53MAPT | |
| SCHEMBL12267532 | 0.71 | LMNA (0.63) | LMNAALDH1A1HDAC6TP53MAPT | |
| SCHEMBL7976489 | 0.70 | LMNA (0.33) | LMNAALDH1A1HDAC6TP53MAPT | |
| SCHEMBL7990538 | 0.70 | LMNA (0.31) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7469010 | 0.66 | DNMT1 (0.53) | LMNAALDH1A1HDAC6SMN1; SMN2GAA | |
| SCHEMBL7470569 | 0.62 | HDAC6 (0.43) | LMNAALDH1A1HDAC6SMN1; SMN2GAA | |
| SCHEMBL7983659 | 0.60 | CYP1A1 (0.40) | LMNAALDH1A1MAPTGAAHTT | |
| SCHEMBL18590264 | 0.60 | SMN1; SMN2 (0.65) | LMNAALDH1A1TP53SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1996-H1 | AGRICULTURE | FMC CORPORATION | 2001-10-02 | — | — | US | disclosed |
| WO-2000031034-A1 | INSECTICIDAL PHOTOSTABLE ACID SALT DERIVATIVES OF N-BENZYL-4-BENZHYDROLPIPERIDINES | FMC CORPORATION (US) | 2000-06-02 | — | — | WO | disclosed |