Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469010 | 0.89 | DNMT1 (0.53) | HDAC6DNMT1EHMT2KCNH2GAA | |
| SCHEMBL7470504 | 0.79 | KCNH2 (0.52) | HDAC6DNMT1EHMT2KCNH2GAA | |
| SCHEMBL7464967 | 0.78 | DNMT1 (0.54) | HDAC6DNMT1EHMT2KCNH2HRH1 | |
| SCHEMBL7990602 | 0.77 | KCNH2 (0.45) | DNMT1EHMT2KCNH2GAAHRH1 | |
| SCHEMBL7465767 | 0.73 | LMNA (0.43) | HDAC6DNMT1EHMT2MEN1KMT2A | |
| SCHEMBL7469624 | 0.72 | KCNH2 (0.61) | DNMT1EHMT2KCNH2HRH1ALDH1A1 | |
| SCHEMBL27627242 | 0.71 | SMN1; SMN2 (0.54) | GAAMEN1KMT2AATMALDH1A1 | |
| SCHEMBL7466544 | 0.71 | ALDH1A1 (0.49) | DNMT1EHMT2KCNH2HRH1ALDH1A1 | |
| SCHEMBL12267532 | 0.71 | LMNA (0.63) | HDAC6KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7990527 | 0.70 | LMNA (0.41) | HDAC6DNMT1EHMT2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0844825-B1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2002-11-27 | — | — | EP | claimed |
| EP-0844825-A4 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORP (US) | 2000-04-05 | — | — | EP | claimed |
| US-6030987-A | Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines | FMC CORPORATION (US) | 2000-02-29 | — | — | US | claimed |
| EP-0844825-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4- BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1998-06-03 | — | — | EP | claimed |
| WO-1996036228-A1 | INSECTICIDAL N-(SUBSTITUTED ARYLMETHYL)-4-[BIS(SUBSTITUTED PHENYL OR PYRIDYL)METHYL]PIPERIDINES | FMC CORPORATION (US) | 1996-11-21 | — | — | WO | claimed |