Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385045 | 0.93 | L3MBTL1 (0.47) | KDM4EALDH1A1GAAMCL1KMT2A | |
| SCHEMBL4385050 | 0.89 | LMNA (0.48) | KDM4EALDH1A1GAAMCL1KMT2A | |
| Oxalic Acid SCHEMBL4394339 | 0.83 | CNR1 (0.42) | KDM4EALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL7990904 | 0.81 | RXFP1 (0.43) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL7989019 | 0.81 | LMNA (0.54) | LMNAHTTUSP2ALOX5PPARG | |
| Oxalic Acid SCHEMBL7994745 | 0.80 | GAA (0.46) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL7971497 | 0.79 | MAPT (0.46) | ALDH1A1GAAKMT2ALMNAHTT | |
| SCHEMBL224970 | 0.79 | LMNA (0.50) | KDM4EKMT2ALMNAHTTMRGPRX4 | |
| SCHEMBL8795871 | 0.79 | GGPS1 (0.37) | — | |
| SCHEMBL4387266 | 0.78 | CHRM5 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |