Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | F2R | P25116 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973194 | 0.89 | FLT1 (0.58) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL7983472 | 0.83 | FLT1 (0.52) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL7990897 | 0.83 | F2R (0.46) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL7991909 | 0.81 | HPGD (0.56) | HPGDPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7973458 | 0.81 | ALDH1A1 (0.49) | HPGDALDH1A1SMN1; SMN2F2RMAPT | |
| SCHEMBL7973398 | 0.79 | KCNA5 (0.41) | HPGDALDH1A1LMNAF2RMAPT | |
| SCHEMBL7987112 | 0.79 | CTSD (0.58) | HPGDALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL7973360 | 0.78 | FLT1 (0.61) | HPGDFLT1FLT4KDRPOLB | |
| SCHEMBL7984835 | 0.78 | HCRTR1 (0.60) | HPGDALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6674926 | 0.78 | FLT1 (0.50) | HPGDFLT1FLT4KDRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |