SCHEMBL7973398

SCHEMBL7973398

CCCS(=O)(=O)NC(=O)c1ccccc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 1/20 0.41
RBP4 P02753 1/20 0.39
CA9 Q16790 4/20 0.38
CA12 O43570 3/20 0.38
SLC6A9 P48067 2/20 0.38
GAA P10253 2/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
LMNA P02545 1/20 0.37
F2R P25116 1/20 0.37
PTPN1 P18031 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ITGB1 P05556 1/20 0.36
ITGA4 P13612 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973486 0.89 LMNA (0.40) KCNA5RBP4CA9CA12GAA
SCHEMBL7990897 0.80 F2R (0.46) KCNA5CA9CA12GAATSHR
SCHEMBL7983472 0.80 FLT1 (0.52) KCNA5SLC6A9GAAF2RMEN1
SCHEMBL7986990 0.80 MYC (0.53) RBP4GAATSHRLMNAKDM4E
SCHEMBL7991909 0.79 HPGD (0.56) GAALMNAF2RKDM4EMEN1
SCHEMBL7990936 0.79 HPGD (0.55) LMNAF2RALDH1A1MAPTHPGD
SCHEMBL7973458 0.79 ALDH1A1 (0.49) KCNA5HTTF2RKDM4EALDH1A1
SCHEMBL7987112 0.77 CTSD (0.58) SLC6A9GAATSHRLMNAMEN1
SCHEMBL7984835 0.75 HCRTR1 (0.60) GAATSHRHTTLMNAKDM4E
SCHEMBL10788700 0.75 TSHR (0.57) GAATSHRHTTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331628-B1 REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed