Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151807 | 0.88 | PYCR1 (0.64) | PYCR1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL842161 | 0.88 | CHRM2 (0.67) | ALDH1A1MEN1KMT2ACHRM2CYP2D6 | |
| SCHEMBL19419957 | 0.81 | MEN1 (0.67) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL28675543 | 0.81 | MEN1 (0.67) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL21878585 | 0.81 | PYCR1 (0.49) | PYCR1MEN1KMT2ACHRM2CYP1A2 | |
| SCHEMBL2552412 | 0.79 | PYCR1 (0.61) | PYCR1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL22882372 | 0.79 | CHRM2 (0.57) | ALDH1A1MEN1KMT2ACHRM2CYP2D6 | |
| SCHEMBL7625869 | 0.79 | HTT (0.63) | MEN1KMT2ACHRM2CYP1A2TDP1 | |
| SCHEMBL28357678 | 0.79 | MEN1 (0.58) | PYCR1MEN1KMT2ACHRM2CYP1A2 | |
| SCHEMBL12437138 | 0.79 | LMNA (0.65) | ALDH1A1MEN1KMT2ACHRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000039055-A1 | RAPID PURIFICATION BY POLYAROMATIC QUENCH REAGENTS | WARNER-LAMBERT COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |