Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006518 | 0.85 | IDO1 (1.00) | IDO1ALDH1A1TDP1CA12CA1 | |
| SCHEMBL197490 | 0.85 | IDO1 (1.00) | IDO1ALDH1A1TDP1CA12CA1 | |
| SCHEMBL29475880 | 0.85 | IDO1 (1.00) | IDO1ALDH1A1TDP1CA12CA1 | |
| SCHEMBL8003575 | 0.81 | IDO1 (0.66) | IDO1ALDH1A1TDP1MAPTMEN1 | |
| 3-Aminophenol SCHEMBL8001729 | 0.80 | ALDH1A1 (0.65) | IDO1ALDH1A1TDP1CA12CA1 | |
| Questiomycin B SCHEMBL8006530 | 0.79 | IDO1 (0.79) | IDO1ALDH1A1TDP1CA12CA1 | |
| SCHEMBL30156557 | 0.76 | IDO1 (0.69) | IDO1ALDH1A1TDP1MAPTMCL1 | |
| SCHEMBL15131699 | 0.76 | IDO1 (0.69) | IDO1ALDH1A1TDP1MAPTMCL1 | |
| SCHEMBL7592067 | 0.76 | IDO1 (0.74) | IDO1ALDH1A1TDP1MAPTMCL1 | |
| SCHEMBL7996107 | 0.76 | IDO1 (0.68) | IDO1ALDH1A1MCL1THRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |